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Engineering processive DNA polymerases with maximum benefit at minimum cost

DNA polymerases need to be engineered to achieve optimal performance for biotechnological applications, which often require high fidelity replication when using modified nucleotides and when replicating difficult DNA sequences. These tasks are achieved for the bacteriophage T4 DNA polymerase by repl...

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Bibliografske podrobnosti
Main Authors: Reha-Krantz, Linda J., Woodgate, Sandra, Goodman, Myron F.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120765/
https://ncbi.nlm.nih.gov/pubmed/25136334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00380
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