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DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase

DNA polymerases achieve high-fidelity DNA replication in part by checking the accuracy of each nucleotide that is incorporated and, if a mistake is made, the incorrect nucleotide is removed before further primer extension takes place. In order to proofread, the primer-end must be separated from the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fidalgo da Silva, Elizabeth, Reha-Krantz, Linda J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018640/
https://ncbi.nlm.nih.gov/pubmed/17702757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm591
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