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DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase
DNA polymerases achieve high-fidelity DNA replication in part by checking the accuracy of each nucleotide that is incorporated and, if a mistake is made, the incorrect nucleotide is removed before further primer extension takes place. In order to proofread, the primer-end must be separated from the...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2018640/ https://ncbi.nlm.nih.gov/pubmed/17702757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm591 |
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