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X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body
O-GlcNAc Transferase (OGT) catalyzes protein O-GlcNAcylation, an abundant and dynamic nuclear and cytosolic modification linked to epigenetic regulation of gene expression. The steady-state levels of O-GlcNAc are influenced by extracellular glucose concentrations suggesting that O-GlcNAcylation may...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120696/ https://ncbi.nlm.nih.gov/pubmed/25136351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00256 |
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