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Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration

Proteostasis is essential in the mammalian brain where post-mitotic cells must function for decades to maintain synaptic contacts and memory. The brain is dependent on glucose and other metabolites for proper function and is spared from metabolic deficits even during starvation. In this review, we o...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Akan, Ilhan, Olivier-Van Stichelen, Stephanie, Bond, Michelle R., Hanover, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735008/
https://ncbi.nlm.nih.gov/pubmed/29049853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14242
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