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Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration

Proteostasis is essential in the mammalian brain where post-mitotic cells must function for decades to maintain synaptic contacts and memory. The brain is dependent on glucose and other metabolites for proper function and is spared from metabolic deficits even during starvation. In this review, we o...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Akan, Ilhan, Olivier-Van Stichelen, Stephanie, Bond, Michelle R., Hanover, John A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735008/
https://ncbi.nlm.nih.gov/pubmed/29049853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14242
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