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Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration

Proteostasis is essential in the mammalian brain where post-mitotic cells must function for decades to maintain synaptic contacts and memory. The brain is dependent on glucose and other metabolites for proper function and is spared from metabolic deficits even during starvation. In this review, we o...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Akan, Ilhan, Olivier-Van Stichelen, Stephanie, Bond, Michelle R., Hanover, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735008/
https://ncbi.nlm.nih.gov/pubmed/29049853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14242
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