Fructokinase activity mediates dehydration-induced renal injury

The epidemic of chronic kidney disease in Nicaragua (Mesoamerican nephropathy) has been linked with recurrent dehydration. Here we tested whether recurrent dehydration may cause renal injury by activation of the polyol pathway, resulting in the generation of endogenous fructose in the kidney that mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Roncal Jimenez, Carlos A, Ishimoto, Takuji, Lanaspa, Miguel A, Rivard, Christopher J, Nakagawa, Takahiko, Ejaz, A. Ahsan, Cicerchi, Christina, Inaba, Shinichiro, Le, MyPhuong, Miyazaki, Makoto, Glaser, Jason, Correa-Rotter, Ricardo, González, Marvin A, Aragón, Aurora, Wesseling, Catharina, Sánchez-Lozada, Laura G, Johnson, Richard J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120672/
https://ncbi.nlm.nih.gov/pubmed/24336030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.492
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