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Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation

Lipids from mycobacteria can be presented to human T cells by group 1 CD1 antigen-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid antigens presented by myeloid dendritic cells, after which they generate anti-bacterial effector functions including IF...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Kawasaki, Norihito, Rillahan, Cory D., Cheng, Tan-Yun, Van Rhijn, Ildiko, Macauley, Matthew S, Moody, D. Branch, Paulson, James C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119498/
https://ncbi.nlm.nih.gov/pubmed/25000981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303278
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