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Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
Lipids from mycobacteria can be presented to human T cells by group 1 CD1 antigen-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid antigens presented by myeloid dendritic cells, after which they generate anti-bacterial effector functions including IF...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119498/ https://ncbi.nlm.nih.gov/pubmed/25000981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303278 |
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