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Co-presentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22
Differentiation of self from non-self is indispensable for maintaining B cell tolerance in peripheral tissues. CD22 and Siglec-G are two inhibitory co-receptors of the BCR that are implicated in maintenance of tolerance to self-antigens. Enforced ligation of CD22 and the BCR by a nanoparticle displa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735655/ https://ncbi.nlm.nih.gov/pubmed/23836061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300921 |
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