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Co-presentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22

Differentiation of self from non-self is indispensable for maintaining B cell tolerance in peripheral tissues. CD22 and Siglec-G are two inhibitory co-receptors of the BCR that are implicated in maintenance of tolerance to self-antigens. Enforced ligation of CD22 and the BCR by a nanoparticle displa...

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Autores principales: Pfrengle, Fabian, Macauley, Matthew S., Kawasaki, Norihito, Paulson, James C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735655/
https://ncbi.nlm.nih.gov/pubmed/23836061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300921
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