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Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells

Infusion of blood cells from a donor can induce humoral tolerance in a recipient and increase the probability of successful organ transplant; a clinical method defined as donor-specific transfusion (DST). Despite the clinical success of DST, the immunological mechanism(s) by which blood cells displa...

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Autors principals: Macauley, Matthew S., Paulson, James C.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201975/
https://ncbi.nlm.nih.gov/pubmed/25252961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401723
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