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Siglec regulation of immune cell function in disease

All mammalian cells display a diverse array of glycan structures that differ from those found on microbial pathogens. Siglecs are a family of sialic acid-binding immunoglobulin-like receptors that participate in the discrimination of ‘self’ and ‘non-self’ and regulate the functions of cells in the i...

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Autori principali: Macauley, Matthew S., Crocker, Paul R., Paulson, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191907/
https://ncbi.nlm.nih.gov/pubmed/25234143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3737
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