Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity

Sialic acid-binding immunoglobulin-like lectins (siglecs) are predominately expressed on immune cells. They are best known as regulators of cell signaling mediated by cytoplasmic tyrosine motifs and are increasingly recognized as receptors for pathogens that bear sialic acid-containing glycans. Most...

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Bibliografiske detaljer
Main Authors: Tateno, Hiroaki, Li, Hongyi, Schur, Melissa J., Bovin, Nicolai, Crocker, Paul R., Wakarchuk, Warren W., Paulson, James C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952126/
https://ncbi.nlm.nih.gov/pubmed/17562860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00383-07
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