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A new mechanism for growth hormone receptor activation of JAK2, and implications for related cytokine receptors
The growth hormone receptor was the first cytokine receptor to be cloned and crystallized, and provides a valuable exemplar for activation of its cognate kinase, JAK2. We review progress in understanding its activation mechanism, in particular the molecular movements made by this constitutively dime...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119067/ https://ncbi.nlm.nih.gov/pubmed/25101218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.29569 |
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