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The Extracellular Domain of the Growth Hormone Receptor Interacts with Coactivator Activator to Promote Cell Proliferation

The presence of GH receptor (GHR) in the cell nucleus correlates with cell division, and targeting the GHR to the nucleus results in constitutive proliferation and transformation because of increased sensitivity to autocrine GH. Here we have sought additional mechanisms that might account for the en...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Conway-Campbell, Becky L., Brooks, Andrew J., Robinson, Philip J., Perani, Michela, Waters, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419461/
https://ncbi.nlm.nih.gov/pubmed/18635665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0128
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