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A new mechanism for growth hormone receptor activation of JAK2, and implications for related cytokine receptors
The growth hormone receptor was the first cytokine receptor to be cloned and crystallized, and provides a valuable exemplar for activation of its cognate kinase, JAK2. We review progress in understanding its activation mechanism, in particular the molecular movements made by this constitutively dime...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Landes Bioscience
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119067/ https://ncbi.nlm.nih.gov/pubmed/25101218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.29569 |
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