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A new mechanism for growth hormone receptor activation of JAK2, and implications for related cytokine receptors
The growth hormone receptor was the first cytokine receptor to be cloned and crystallized, and provides a valuable exemplar for activation of its cognate kinase, JAK2. We review progress in understanding its activation mechanism, in particular the molecular movements made by this constitutively dime...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119067/ https://ncbi.nlm.nih.gov/pubmed/25101218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.29569 |
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