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Murine Cirrhosis Induces Hepatocyte Epithelial Mesenchymal Transition and Alterations in Survival Signaling Pathways

Hepatocytes that reside in a chronically-injured liver have altered growth responses compared to hepatocytes in normal liver. Transforming growth factor beta (TGFβ) is upregulated in the cirrhotic liver, and cirrhotic hepatocytes, unlike normal hepatocytes exposed to this cytokine, exhibit decreased...

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Autors principals: Nitta, Takashi, Kim, Jae-Sung, Mohuczy, Dagmara, Behrns, Kevin E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118693/
https://ncbi.nlm.nih.gov/pubmed/18712785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22397
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