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Hepatocytes Do Not Undergo Epithelial-Mesenchymal Transition in Liver Fibrosis in Mice

The origin of fibrogenic cells in liver fibrosis remains controversial. We assessed the emerging concept that hepatocytes contribute to production of extracellular matrix (ECM) in liver fibrosis through epithelial-mesenchymal transition (EMT). We bred triple transgenic mice expressing ROSA26 stop β-...

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Detalhes bibliográficos
Main Authors: Taura, Kojiro, Miura, Kouichi, Iwaisako, Keiko, Österreicher, Christoph H, Kodama, Yuzo, Penz-Österreicher, Melitta, Brenner, David A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906231/
https://ncbi.nlm.nih.gov/pubmed/20052656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23368
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