JNK1 from Hematopoietic Cells Mediates Progression from Hepatic Steatosis to Steatohepatitis and Fibrosis in Mice

BACKGROUND & AIMS: c-Jun N-terminal kinase (JNK) plays a pivotal role in the development of the metabolic syndrome including NAFLD. However, the mechanism underlying the contribution of JNK to the progression from simple steatosis to steatohepatitis and liver fibrosis is unresolved. METHODS: Hep...

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主要な著者: Kodama, Yuzo, Kisseleva, Tatiana, Iwaisako, Keiko, Miura, Kouichi, Taura, Kojiro, De Minicis, Samuele, Österreicher, Christoph H., Schnabl, Bernd, Seki, Ekihiro, Brenner, David A.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757473/
https://ncbi.nlm.nih.gov/pubmed/19549522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.06.045
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