Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

BACKGROUND & AIMS: Development of nonalcoholic steatohepatitis (NASH) involves the innate immune system and is mediated by Kupffer cells and hepatic stellate cells (HSCs). Toll-like receptor 9 (TLR9) is a pattern recognition receptor that recognizes bacteria-derived cytosine phosphate guanine (C...

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Publicado no:Gastroenterology
Main Authors: MIURA, KOUICHI, KODAMA, YUZO, INOKUCHI, SAYAKA, SCHNABL, BERND, AOYAMA, TOMONORI, OHNISHI, HIROHIDE, OLEFSKY, JERROLD M., BRENNER, DAVID A., SEKI, EKIHIRO
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631262/
https://ncbi.nlm.nih.gov/pubmed/20347818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.03.052
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