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Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

Inflammatory cell infiltration in the liver is a hallmark of nonalcoholic steatohepatitis (NASH). The chemokine-chemokine receptor interaction induces inflammatory cell recruitment. CC-chemokine receptor (CCR)2 is expressed on hepatic macrophages and hepatic stellate cells. This study aims to invest...

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Main Authors: Miura, Kouichi, Yang, Ling, van Rooijen, Nico, Ohnishi, Hirohide, Seki, Ekihiro
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378163/
https://ncbi.nlm.nih.gov/pubmed/22442158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00365.2011
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