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Impaired Autophagy: A Mechanism of Mitochondrial Dysfunction in Anoxic Rat Hepatocytes

Autophagy selectively removes abnormal or damaged organelles such as dysfunctional mitochondria. The mitochondrial permeability transition (MPT) is a marker of impaired mitochondrial function that is evident in hepatic ischemia/reperfusion (I/R) injury. However, the relationship between mitochondria...

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Autores principales: Kim, Jae-Sung, Nitta, Takashi, Mohuczy, Dagmara, O'Malley, Kerri A., Moldawer, Lyle L., Dunn, William A., Behrns, Kevin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971577/
https://ncbi.nlm.nih.gov/pubmed/18311843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22187
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