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Age-associated changes in human CD4(+) T cells point to mitochondrial dysfunction consequent to impaired autophagy
To gain understanding on the mechanisms that drive immunosenescence in humans, we examined CD4(+) T cells obtained from younger (20-39 years-old) and older (70+ years-old) healthy participants of the Baltimore Longitudinal Study on Aging (BLSA). We found that mitochondrial proteins involved in the e...
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| Publicat a: | Aging (Albany NY) |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874450/ https://ncbi.nlm.nih.gov/pubmed/31707363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102438 |
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