Parathyroid Hormone Regulates Histone Deacetylase (HDAC) 4 through Protein Kinase A-mediated Phosphorylation and Dephosphorylation in Osteoblastic Cells

Histone deacetylases (HDACs) are crucial regulators of gene expression in transcriptional co-repressor complexes. Previously, we reported that HDAC4 was a basal repressor of matrix metalloproteinase-13 (MMP-13) transcription and parathyroid hormone (PTH) regulates HDAC4 to control MMP-13 promoter ac...

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Detalhes bibliográficos
Main Authors: Shimizu, Emi, Nakatani, Teruyo, He, Zhiming, Partridge, Nicola C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118099/
https://ncbi.nlm.nih.gov/pubmed/24904057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550699
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