HDAC4 Represses Matrix Metalloproteinase-13 Transcription in Osteoblastic Cells, and Parathyroid Hormone Controls This Repression

Parathyroid hormone (PTH) is a hormone regulating bone remodeling through its actions on both bone formation and bone resorption. Previously we reported that PTH induces matrix metalloproteinase-13 (MMP-13) transcription in osteoblastic cells. Here, we show that histone deacetylase 4 (HDAC4) interac...

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Detalhes bibliográficos
Main Authors: Shimizu, Emi, Selvamurugan, Nagarajan, Westendorf, Jennifer J., Olson, Eric N., Partridge, Nicola C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843211/
https://ncbi.nlm.nih.gov/pubmed/20097749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094862
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