Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

ABSTRACT: Mitochondrial ferritin is a functional ferritin that localizes in the mitochondria. It is expressed in the testis, heart, brain, and cells with active respiratory activity. Its overexpression in cultured cells protected against oxidative damage and reduced cytosolic iron availability. Howe...

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Bibliographische Detailangaben
Hauptverfasser: Maccarinelli, Federica, Gammella, Elena, Asperti, Michela, Regoni, Maria, Biasiotto, Giorgio, Turco, Emilia, Altruda, Fiorella, Lonardi, Silvia, Cornaghi, Laura, Donetti, Elena, Recalcati, Stefania, Poli, Maura, Finazzi, Dario, Arosio, Paolo, Cairo, Gaetano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118045/
https://ncbi.nlm.nih.gov/pubmed/24728422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1147-0
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