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Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects

Iron is essential for life, while also being potentially harmful. Therefore, its level is strictly monitored and complex pathways have evolved to keep iron safely bound to transport or storage proteins, thereby maintaining homeostasis at the cellular and systemic levels. These sequestration mechanis...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Gammella, Elena, Recalcati, Stefania, Cairo, Gaetano
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783558/
https://ncbi.nlm.nih.gov/pubmed/27006749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8629024
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