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Iron Availability in Tissue Microenvironment: The Key Role of Ferroportin
Body iron levels are regulated by hepcidin, a liver-derived peptide that exerts its function by controlling the presence of ferroportin (FPN), the sole cellular iron exporter, on the cell surface. Hepcidin binding leads to FPN internalization and degradation, thereby inhibiting iron release, in part...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7999357/ https://ncbi.nlm.nih.gov/pubmed/33804198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062986 |
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