Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

ABSTRACT: Mitochondrial ferritin is a functional ferritin that localizes in the mitochondria. It is expressed in the testis, heart, brain, and cells with active respiratory activity. Its overexpression in cultured cells protected against oxidative damage and reduced cytosolic iron availability. Howe...

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Main Authors: Maccarinelli, Federica, Gammella, Elena, Asperti, Michela, Regoni, Maria, Biasiotto, Giorgio, Turco, Emilia, Altruda, Fiorella, Lonardi, Silvia, Cornaghi, Laura, Donetti, Elena, Recalcati, Stefania, Poli, Maura, Finazzi, Dario, Arosio, Paolo, Cairo, Gaetano
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2014
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118045/
https://ncbi.nlm.nih.gov/pubmed/24728422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1147-0
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