Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

ABSTRACT: Mitochondrial ferritin is a functional ferritin that localizes in the mitochondria. It is expressed in the testis, heart, brain, and cells with active respiratory activity. Its overexpression in cultured cells protected against oxidative damage and reduced cytosolic iron availability. Howe...

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Detalhes bibliográficos
Main Authors: Maccarinelli, Federica, Gammella, Elena, Asperti, Michela, Regoni, Maria, Biasiotto, Giorgio, Turco, Emilia, Altruda, Fiorella, Lonardi, Silvia, Cornaghi, Laura, Donetti, Elena, Recalcati, Stefania, Poli, Maura, Finazzi, Dario, Arosio, Paolo, Cairo, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118045/
https://ncbi.nlm.nih.gov/pubmed/24728422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1147-0
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