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Structural studies of CNG repeats

CNG repeats (where N denotes one of the four natural nucleotides) are abundant in the human genome. Their tendency to undergo expansion can lead to hereditary diseases known as TREDs (trinucleotide repeat expansion disorders). The toxic factor can be protein, if the abnormal gene is expressed, or th...

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Bibliografske podrobnosti
Main Authors: Kiliszek, Agnieszka, Rypniewski, Wojciech
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117766/
https://ncbi.nlm.nih.gov/pubmed/24939898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku536
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