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Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor
To our knowledge, no structural study to date has characterized, in an intact receptor, the coupling of conformational change in extracellular domains through a single-pass transmembrane domain to conformational change in cytoplasmic domains. Here we examine such coupling, and its unexpected complex...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117315/ https://ncbi.nlm.nih.gov/pubmed/21822280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2092 |
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