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Hypoxia and Glucocorticoid Signaling Converge to Regulate Macrophage Migration Inhibitory Factor Gene Expression

OBJECTIVE: Macrophage migration inhibitory factor (MIF) is a proinflammatory mediator involved in the pathogenesis of rheumatoid arthritis. This study was undertaken to identify the MIF promoter elements responsible for regulating gene expression. METHODS: Luciferase reporter gene assays were used t...

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Hlavní autoři: Elsby, Laura M., Donn, Rachelle, Alourfi, Zaynab, Green, Laura M., Beaulieu, Elaine, Ray, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116773/
https://ncbi.nlm.nih.gov/pubmed/19644855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24659
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