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Macrophage migration inhibitory factor promotes resistance to glucocorticoid treatment in EAE

OBJECTIVE: Glucocorticoids (GCs) are used as standard treatment for acute attacks of multiple sclerosis (MS). However, GCs eventually lose efficacy and do not prevent disease progression. Macrophage migration inhibitory factor (MIF) is the only known proinflammatory cytokine induced by GCs that inhi...

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Bibliographic Details
Published in:Neurol Neuroimmunol Neuroinflamm
Main Authors: Ji, Niannian, Kovalovsky, Andra, Fingerle-Rowson, Günter, Guentzel, M. Neal, Forsthuber, Thomas G.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529283/
https://ncbi.nlm.nih.gov/pubmed/26280015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000139
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