Macrophage Migration Inhibitory Factor inhibits the anti-inflammatory effects of glucocorticoids via glucocorticoid-induced leucine zipper

OBJECTIVES: Glucocorticoids remain a mainstay of the treatment of rheumatoid arthritis (RA). Dose-dependent adverse effects highlight the potential for therapies that regulate glucocorticoid sensitivity to enable glucocorticoid dose reduction. Macrophage migration inhibitory factor (MIF) is a pro-in...

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Main Authors: Fan, Huapeng, Kao, Wenping, Yang, Yuan H., Gu, Ran, Harris, James, Fingerle-Rowson, Günter, Bucala, Richard, Ngo, Devi, Beaulieu, Elaine, Morand, Eric F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116443/
https://ncbi.nlm.nih.gov/pubmed/24782327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38689
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