Identification of a novel cell type-specific intronic enhancer of macrophage migration inhibitory factor (MIF) and its regulation by mithramycin

The aim of this study was to determine the genetic regulation of macrophage migration inhibitory factor (MIF). DNase I hypersensitivity was used to identify potential hypersensitive sites (HS) across the MIF gene locus. Reporter gene assays were performed in different human cell lines with construct...

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Bibliographic Details
Main Authors: Beaulieu, E, Green, L, Elsby, L, Alourfi, Z, Morand, E F, Ray, D W, Donn, R
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Translational Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043308/
https://ncbi.nlm.nih.gov/pubmed/21087445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04289.x
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