Decitabine reactivated pathways in platinum resistant ovarian cancer

Combination therapy with decitabine, a DNMTi and carboplatin resensitized chemoresistant ovarian cancer (OC) to platinum inducing promising clinical activity. We investigated gene-expression profiles in tumor biopsies to identify decitabine-reactivated pathways associated with clinical response. Gen...

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Bibliografiske detaljer
Main Authors: Fang, Fang, Zuo, Qingyao, Pilrose, Jay, Wang, Yinu, Shen, Changyu, Li, Meng, Wulfridge, Phillip, Matei, Daniela, Nephew, Kenneth P.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116504/
https://ncbi.nlm.nih.gov/pubmed/25003579
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