IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells

In high-grade serous ovarian cancer (OC), chemotherapy eliminates the majority of tumor cells, leaving behind residual tumors enriched in OC stem cells (OCSC). OCSC, defined as aldehyde dehydrogenase–positive (ALDH(+)), persist and contribute to tumor relapse. Inflammatory cytokine IL-6 is elevated...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Wang, Yinu, Zong, Xingyue, Mitra, Sumegha, Mitra, Anirban Kumar, Matei, Daniela, Nephew, Kenneth P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328027/
https://ncbi.nlm.nih.gov/pubmed/30518684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122360
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