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Epigenetic Resensitization to Platinum in Ovarian Cancer

Preclinical studies have shown that hypomethylating agents reverse platinum resistance in ovarian cancer. In this phase II clinical trial, based upon the results of our phase I dose defining study, we tested the clinical and biologic activity of low-dose decitabine administered before carboplatin in...

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Detalhes bibliográficos
Main Authors: Matei, Daniela, Fang, Fang, Shen, Changyu, Schilder, Jeanne, Arnold, Alesha, Zeng, Yan, Berry, William A., Huang, Tim, Nephew, Kenneth P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700422/
https://ncbi.nlm.nih.gov/pubmed/22549947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3909
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