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Moderate, chronic ethanol feeding exacerbates carbon tetrachloride–induced hepatic fibrosis via hepatocyte-specific hypoxia-inducible factor 1α

The hypoxia-sensing transcriptional factor HIF1α is implicated in a variety of hepato-pathological conditions; however, the contribution of hepatocyte-derived HIF1α during progression of alcoholic liver injury is still controversial. HIF1α induces a variety of genes including those involved in apopt...

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Bibliografiske detaljer
Main Authors: Roychowdhury, Sanjoy, Chiang, Dian J, McMullen, Megan R, Nagy, Laura E
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115456/
https://ncbi.nlm.nih.gov/pubmed/25089199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.61
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