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Function and regulation of the Rho guanine nucleotide exchange factor Trio

Rho GTPases oscillate between an inactive GDP-bound state and an active GTP-bound state. They are activated by Rho Guanine nucleotide Exchange Factors (GEF), which accelerate the GDP to GTP exchange. RhoGEFs fall into two different classes: the Dbl family and the DOCK family of proteins. In this rev...

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Hlavní autoři: Schmidt, Susanne, Debant, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114922/
https://ncbi.nlm.nih.gov/pubmed/24987837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.29769
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