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Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway.

We report here that the activation of the interleukin 1 beta (IL-1 beta)-converting enzyme (ICE) family is likely to be one of the crucial events of tumor necrosis factor (TNF) cytotoxicity. The cowpox virus CrmA protein, a member of the serpin superfamily, inhibits the enzymatic activity of ICE and...

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Bibliografische gegevens
Hoofdauteurs: Miura, M, Friedlander, R M, Yuan, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41148/
https://ncbi.nlm.nih.gov/pubmed/7667287
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