DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

Previously we reported the development of a plasmid DNA expression vector system derived from Sindbis virus (T. W. Dubensky, Jr., et al., J. Virol. 70:508–519, 1996). In vitro, such vectors exhibit high-level heterologous gene expression via self-amplifying cytoplasmic RNA replication. In the presen...

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Hauptverfasser: Hariharan, Mangala J., Driver, David A., Townsend, Kay, Brumm, Duane, Polo, John M., Belli, Barbara A., Catton, Donald J., Hsu, David, Mittelstaedt, Denise, McCormack, James E., Karavodin, Linda, Dubensky, Thomas W., Chang, Stephen M. W., Banks, Theresa A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Viral Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124565/
https://ncbi.nlm.nih.gov/pubmed/9444987
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