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DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

Previously we reported the development of a plasmid DNA expression vector system derived from Sindbis virus (T. W. Dubensky, Jr., et al., J. Virol. 70:508–519, 1996). In vitro, such vectors exhibit high-level heterologous gene expression via self-amplifying cytoplasmic RNA replication. In the presen...

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Detalhes bibliográficos
Main Authors: Hariharan, Mangala J., Driver, David A., Townsend, Kay, Brumm, Duane, Polo, John M., Belli, Barbara A., Catton, Donald J., Hsu, David, Mittelstaedt, Denise, McCormack, James E., Karavodin, Linda, Dubensky, Thomas W., Chang, Stephen M. W., Banks, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124565/
https://ncbi.nlm.nih.gov/pubmed/9444987
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