DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

Previously we reported the development of a plasmid DNA expression vector system derived from Sindbis virus (T. W. Dubensky, Jr., et al., J. Virol. 70:508–519, 1996). In vitro, such vectors exhibit high-level heterologous gene expression via self-amplifying cytoplasmic RNA replication. In the presen...

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Main Authors: Hariharan, Mangala J., Driver, David A., Townsend, Kay, Brumm, Duane, Polo, John M., Belli, Barbara A., Catton, Donald J., Hsu, David, Mittelstaedt, Denise, McCormack, James E., Karavodin, Linda, Dubensky, Thomas W., Chang, Stephen M. W., Banks, Theresa A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Viral Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124565/
https://ncbi.nlm.nih.gov/pubmed/9444987
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