DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

Previously we reported the development of a plasmid DNA expression vector system derived from Sindbis virus (T. W. Dubensky, Jr., et al., J. Virol. 70:508–519, 1996). In vitro, such vectors exhibit high-level heterologous gene expression via self-amplifying cytoplasmic RNA replication. In the presen...

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Bibliographic Details
Main Authors: Hariharan, Mangala J., Driver, David A., Townsend, Kay, Brumm, Duane, Polo, John M., Belli, Barbara A., Catton, Donald J., Hsu, David, Mittelstaedt, Denise, McCormack, James E., Karavodin, Linda, Dubensky, Thomas W., Chang, Stephen M. W., Banks, Theresa A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124565/
https://ncbi.nlm.nih.gov/pubmed/9444987
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