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Alcohol Selectivity of β3-Containing GABA(A) Receptors: Evidence for a Unique Extracellular Alcohol/Imidazobenzodiazepine Ro15-4513 Binding Site at the α+β− Subunit Interface in αβ3δ GABA(A) Receptors

GABA(A) receptors (GABARs) have long been the focus for acute alcohol actions with evidence for behaviorally relevant low millimolar alcohol actions on tonic GABA currents and extrasynaptic α4/6, δ, and β3 subunit-containing GABARs. Using recombinant expression in oocytes combined with two electrode...

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Detalhes bibliográficos
Main Authors: Wallner, M., Hanchar, H. J., Olsen, R. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114768/
https://ncbi.nlm.nih.gov/pubmed/24500446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-014-1243-0
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