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Alcohol Selectivity of β3-Containing GABA(A) Receptors: Evidence for a Unique Extracellular Alcohol/Imidazobenzodiazepine Ro15-4513 Binding Site at the α+β− Subunit Interface in αβ3δ GABA(A) Receptors

GABA(A) receptors (GABARs) have long been the focus for acute alcohol actions with evidence for behaviorally relevant low millimolar alcohol actions on tonic GABA currents and extrasynaptic α4/6, δ, and β3 subunit-containing GABARs. Using recombinant expression in oocytes combined with two electrode...

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Autori principali: Wallner, M., Hanchar, H. J., Olsen, R. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114768/
https://ncbi.nlm.nih.gov/pubmed/24500446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-014-1243-0
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