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Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABA(A) receptors as an opportunity for drug development?

Alcohol (ethanol, EtOH) has pleiotropic actions and induces a number of acute and long-term effects due to direct actions on alcohol targets, and effects of alcohol metabolites and metabolism. Many detrimental health consequences are due to EtOH metabolism and metabolites, in particular acetaldehyde...

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Autores principales: Wallner, M, Olsen, R W
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442438/
https://ncbi.nlm.nih.gov/pubmed/18278063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.32
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