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Defining the Factors That Contribute to On-Target Specificity of Antisense Oligonucleotides
To better understand the factors that influence the activity and specificity of antisense oligonucleotides (ASOs), we designed a minigene encoding superoxide dismutase 1 (SOD-1) and cloned the minigene into vectors for T7 transcription of pre-mRNA and splicing in a nuclear extract or for stable inte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114480/ https://ncbi.nlm.nih.gov/pubmed/25072142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101752 |
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