PAS Kinase Drives Lipogenesis Through SREBP-1 Maturation

Elevated hepatic synthesis of fatty acids and triglycerides, driven by hyperactivation of the SREBP-1c transcription factor, has been implicated as a causal feature of the metabolic syndrome. SREBP-1c activation requires the proteolytic maturation of the endoplasmic reticulum-bound precursor to the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Xiaoying, Romero, Donna, Swiatek, Wojciech I., Dorweiler, Irene, Kikani, Chintan K., Sabic, Hana, Zweifel, Ben S., McKearn, John, Blitzer, Jeremy T., Nickols, G. Allen, Rutter, Jared
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112965/
https://ncbi.nlm.nih.gov/pubmed/25001282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados